Vitamin B6

Vitamin B-6 is an important compound found in many foods. Because it plays such a vital role in the body taking it as a supplement is wise for those who don’t get enough in their diets.

vitamin b6


  • Improves overall attentiveness and has been used to help treat ADHD [4]
  • Increases dream vividness and dream recall [1]
  • Decreases Risk of Parkinson’s disease by up to 50% [2]
  • Prevents heart disease [3]
  • Alleviates hangovers and morning sickness [5]
  • Decreases the risk of cancer [6]

What Is Vitamin B6?

Vitamin B-6 is a water soluble compound that is known to come in several different forms.  It was discovered in 1934 by a Hungarian physician, Paul Gyorgy. He named it B-6 after curing a skin disease in rats with the compound. We now know that vitamin B-6 can be obtained from a variety of foods including meats, whole grain products, vegetables, nuts, and bananas. Vitamin B-6 is sold as a supplement all over the world because of its many benefits.

Vitamin B6 Dosage Information

Below is a chart for recommended daily intake for vitamin-B6. If you are lacking this amount in your diet then it is strongly recommended that you take a supplement. Vitamin-B6 deficiency is linked to many disorders including atrophic glossitis, angular cheilitis, and other neuropathic disorders. [7] You can view the amount of vitamin-B6 present in different foods here. Even though it is perfectly safe to go over these recommended dosages the US FDA has set 100mg/day as the tolerable upper limit. [8]

How Does Vitamin B6 Work?

Vitamin B-6 has many different jobs in multiple places throughout the body. Its functions include:

  • Macronutrient metabolism
  • Lipid metabolism
  • Synthesis of certain neurotransmitters
  • Histamine synthesis
  • Hemoglobin synthesis
  • Gene expression
  • Facilitates gluconeogenesis

Safety and Side Effects of Vitamin B6

Vitamin B-6 is regarded as completely safe and there has never been a documented adverse effect from food sources.  At doses above recommended intake from oral supplements side effects have occasionally included nausea, loss of appetite, headache, and sleepiness. Long-term usage at doses exceeding 500mg/day has been linked to certain brain and nerve disorders.  Be cautious if you are taking vitamin-B6 with Amidarone, Phenobarbital, or Phenytoin as B-6 could decrease their effectiveness and lead to additional side effects.


Vitamin B6 FAQ

Below are some of the most commonly asked questions about Vitamin B6. If you have a question that’s not on this list, send it to us at and we will answer it for you.

Should I Use Vitamin B6?

What Are Some Notable Vitamin B6 Studies?

Cited Studies

1.  Ebben, M., Lequerica, A., & Spielman A. (2002). Effects of pyridoxine on dreaming: a preliminary study. Perceptual & Motor Skills, 94(1), 135–140.

2.  Increased intake of vitamin B6Sheet”. Retrieved 2006-08-11.

3. TLC Cooking “Benefits of Vitamin B6″

4. Mousain-Bosc M et al. (2006). “Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. I. Attention deficit hyperactivity disorders.”. Magnesium Research 19 (1): 46–52. PMID 16846100.

5.  THE MYSTERIOUS VITAMIN B6. By Dr. Russ Ebbets. Off The Road Column

6.  Larsson, S. JAMA 2010; 303:1077-1083.

7. Andrews’ Diseases of the Skin, 10th Edition, Elsevier.

8. The EFSA Journal (2008) 760, 1-13

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